关于边缘性牙周炎的病因主要是生息在牙齦沟内的细菌。细菌对牙周组织的损伤机理非常复杂。作为菌体成份特別是菌体内毒素和细菌酶,目前引起了极大的重视。在细菌酶中,特别是细菌的硫酸软骨素酶和透明质酸酶对牙周组织的破坏至为重要。 本研究目的为明确细菌酶如何引起牙周组织的破坏,对边缘性牙周炎患者的牙齦组织中的细菌软骨素 About the causes of marginal periodontitis are mainly bacteria that inhabit the gingival sulcus. The mechanism of bacterial damage to periodontal tissues is very complex. As bacterial cell components, especially bacterial toxins and bacterial enzymes, has caused great attention. In bacterial enzymes, especially bacterial chondroitinase and hyaluronidase damage to the periodontal tissue is crucial. The purpose of this study is to clarify how bacterial enzymes can cause the destruction of periodontal tissues, and to treat bacterial chondroitin in gingival tissues of patients with marginal periodontitis