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羧苄青霉素(CBPC)是治疗革兰氏阴性菌特别是绿脓杆菌感染肯定有效的抗生素,但若大剂量静脉内给药,则往往产生毒性,因而有必要寻找抗菌谱相似而活性更强的新抗生素。为此,本文报道了硫苯咪唑青霉素(MZPC)对临床分离的各种革兰氏阴性菌的抗菌活性,并与CBPC、羧噻吩青霉素(TI-PC)、苯咪唑青霉素(AZPC)比较,也与苄青霉素和氨苄青霉素(ABPC)作了适当的比较。收集临床分离的各种病原菌,采用Ox-oid的Isosensitest琼脂和Isosensitest肉汤培养。对不同菌株生长还适当添加了各种物
Carbapenem (CBPC) is an effective antibiotic for the treatment of Gram-negative bacteria, especially Pseudomonas aeruginosa infection. However, if large doses of intravenous injection are used, they often produce toxicity. Therefore, it is necessary to find a more active and active antimicrobial spectrum New antibiotics. Therefore, the antibacterial activity of benzimidazole penicillin (MZPC) against clinically isolated Gram-negative bacteria was reported and compared with CBPC, TI-PC and AZPC Appropriate comparisons with ampicillin and ampicillin (ABPC). Various clinically isolated pathogens were collected, grown on Isosensitest agar with Ox-oid and Isosensitest broth. Different strains of growth is also appropriate to add a variety of things