Because of the unclearness of traditional hematoxylin-eosin stain and toxicity of phloxine-tartmine stain for detection of paneth cell,a new clear and time saving method was proposed.The specimen was first stained with a modification of Mayer’s H-E staining[1] and Because of the unclearness of traditional hematoxylin-eosin stain and toxicity of phloxine-tartmine stain for detection of paneth cell, a new clear and time saving method was proposed. The specimen was first stained with a modification of Mayer’s H-E staining [1] and