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随着胸外科的发展,胸部手术中各种因素导致的急性肺损伤(ALI),已日益引起临床工作者的重视。术中肺缺血-再灌注损伤、肺组织的切除、术中麻醉药、输血、补液、通气方式等因素会导致ALI,而缩短阻断时间、缺血预处理、药物干预、术中注意等积极的预防能避免或减少ALI的发生。ALI的治疗包括机械通气、一氧化氮吸入、表面活性物质替代治疗、免疫治疗、药物治疗、血液净化、体外循环膜肺氧合及支气管肺泡灌洗等,文章就胸部手术中的ALI予以综述。
With the development of thoracic surgery, acute lung injury (ALI) caused by various factors in chest surgery has drawn increasing attention from clinicians. Intraoperative pulmonary ischemia-reperfusion injury, lung resection, intraoperative anesthesia, transfusion, rehydration, ventilation and other factors will lead to ALI, and shorten the blocking time, ischemic preconditioning, drug intervention, intraoperative attention Active prevention can prevent or reduce the occurrence of ALI. The treatment of ALI includes mechanical ventilation, nitric oxide inhalation, surfactant replacement therapy, immunotherapy, drug therapy, blood purification, cardiopulmonary bypass cardiopulmonary bypass and bronchoalveolar lavage, the article reviews the ALI in chest surgery.