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透明质酸(HA)是一种高分子氨基多糖,由体内各组织间质细胞合成,在肝内皮细胞进行降解。已有报道HA是肝脏损伤的灵敏指标,肝病时HA升高,糖尿病(DM)患者常合并多种脏器的慢性病变,其DM性肝病是DM的一种慢性合并症。目前,有关DM引起肝脏病变的报道较少,其诊断主要依靠病理学检查。本文采用放射免疫分析法(RIA)测定112名健康人及104名DM患者血清HA的含量,以探讨对DM性肝病诊断的临床价值。 材料和方法 一、对象: (一)正常对照组:为本院健康职工及健康体检者112例(男57,女55)。年龄54.6±10.0岁。
Hyaluronic acid (HA) is a kind of macromolecule amino polysaccharide synthesized by interstitial cells of various tissues in the body and degraded in the liver endothelial cells. It has been reported that HA is a sensitive indicator of liver injury, elevated HA in liver disease, and chronic diabetic patients (DM) are often complicated by multiple organs. DM is a chronic complication of DM. At present, there are few reports about DM-induced liver lesion, and its diagnosis mainly depends on pathological examination. In this paper, radioimmunoassay (RIA) determination of serum levels of 112 healthy subjects and 104 DM patients to explore the clinical value of the diagnosis of DM liver disease. Materials and methods First, the object: (A) normal control group: 112 healthy workers and health examination in our hospital (male 57, female 55). Age 54.6 ± 10.0 years.