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C_3是补体系统中含量最高、功能最复杂的成分,也是连接经典途径与替代途径的枢纽.完整的C_3分子蕴藏着多种功能结构,被C_3转化酶分解之后,便逐次暴露出来,表现重要的生物学功能.C_3b是补体系统最重要的活性片段,既是机体防御屏障的要素,又是某些重要的补体酶的组成部分.新生的C_3b一方面共价结合于微生物或免疫复合物(IC),另一方面又作为配体与细胞
C_3 is the most abundant and most complex component in the complement system, and also a link between the classical pathway and the alternative pathway. The complete C_3 molecule contains a variety of functional structures, and is decomposed by the C_3 invertase, Biological function.C_3b is the most important active fragment of the complement system, which is not only an important factor in the body’s defense barrier, but also a component of some important complement enzymes.The newborn C_3b covalently binds to microorganisms or immune complexes (ICs) , On the other hand as ligands and cells