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目的分析肺肉瘤样癌的临床病理特征。方法分析42例肺肉瘤样癌的临床病理及免疫组化情况。结果术后病理证实梭形细胞癌1例,巨细胞癌1例,癌肉瘤4例,多形性癌36例。均由上皮成分和肉瘤样成分组成。免疫组化结果显示24例行细胞角蛋白(CK)检测均(+);20例自身免疫性心肌炎(EMA)检测,18例(+);25例行波形蛋白(Vim)检测,均(+)。随访结果18例生存,平均生存时间13.3个月,1年生存率61.2%。结论肺肉瘤样癌的诊断仍需依靠病理检查结果,免疫组化有助于确诊。
Objective To analyze the clinicopathological features of pulmonary sarcomatoid carcinoma. Methods 42 cases of sarcomatoid carcinoma of the clinicopathological and immunohistochemical analysis. Results Postoperative pathology confirmed spindle cell carcinoma in 1, giant cell carcinoma in 1, carcinosarcoma in 4, and pleomorphic carcinoma in 36. Both composed of epithelial and sarcomatoid components. Immunohistochemical results showed that cytokeratin (CK) was detected in 24 cases (+), 20 cases of autoimmune myocarditis (EMA), 18 cases (+) and 25 cases of Vim. ). Follow-up results 18 cases of survival, the average survival time of 13.3 months, 1-year survival rate of 61.2%. Conclusion The diagnosis of pulmonary sarcomatoid carcinoma still depends on the results of pathological examination, and immunohistochemistry is helpful for the diagnosis.