为了探讨反映血吸虫病性肝纤维化程度的指标和各参数之间的相关性。我们用生化学和病理学方法对肝胶原量、肝纤维束宽度、肝虫卵数、血、尿羟脯氨酸含量以及血清蛋白比例进行了检测。 材料和方法 以家兔77只为实验动物.其中65只分别接种尾蚴200±5条,另12只作不接种对照组。接种兔15周后取肝组织,65只中53只作下述检测。 一、肝胶原量测定 采用Neuman法,略加改进。 二、肝病变的大体观察 肝正常者表面光滑, In order to explore the index of schistosomiasis-induced liver fibrosis and the correlation between the parameters. We used biochemical and pathological methods to detect the quantity of hepatic collagen, the width of hepatic fibrosis, the number of eggs, the content of serum hydroxyproline, the content of serum hydroxyproline and serum protein. MATERIALS AND METHODS: Totally 77 rabbits were used as experimental animals, of which 65 were inoculated with 200 ± 5 cercariae respectively and the other 12 were not inoculated with control group. The rabbits were sacrificed at 15 weeks after inoculation, and 53 out of 65 were tested as follows. First, the determination of hepatic collagen using Neuman method, a slight improvement. Second, the general observation of liver disease normal liver surface smooth,