根据川西南威远气田大水量气井现场测试数据，建立了举升油管和油套环空气液两相流压降优化模型。将油管内的持液率模化为气相、液相无因次速度和液相无因次粘度的函数；环空流动的持液率模化为气相与液相折算速度、密度和粘度三个相对量的函数。以最小计算压降与实测值的平均绝对误差作为目标函数，优化持液率关系式的参数值和管壁粗糙度修正系数。经综合评价表明，对于大水量气井条件下，新模型的计算结果与现场数据十分吻合，其性能明显优于所比较的５个常用经验相关式。文中还对此模型进行了水气比敏感性分析 According to the field test data of large-volume gas wells in Weiyuan gas field in southwestern Sichuan, a pressure drop optimization model of air-liquid two-phase flow in lifting oil pipe and oil collar was established. The liquid holdups in the tubing were modeled as a function of the gas phase, the non-dimensional velocity of the liquid phase and the non-dimensional viscosity of the liquid phase. The holdup of the annulus flow was modeled as the gas-liquid phase velocity, the density and the viscosity Relative amount of function. Taking the average absolute error between the minimum calculated pressure drop and the measured value as the objective function, the parameter value of the liquid holdup ratio and the correction coefficient of the pipe wall roughness are optimized. The comprehensive evaluation shows that the calculation results of the new model are in good agreement with the field data for large water volume well conditions, and their performance is obviously better than the five commonly used empirical correlation formulas. The model is also analyzed for water vapor sensitivity