新生儿破伤风(Neonatal tetanus,NT)是接生断脐时,消毒不严,致破伤风杆菌通过脐部进入机体,产生痉挛毒素可沿淋巴液、神经干等传至脊髓和脑干,与中枢神经组织中神经节苷脂结合,使后者不能释放抑制性神经介质,从而引起牙关紧闭及全身肌肉强烈持续收缩的一种急性感染性疾病[1]。通常在生后的4～7 d发病,故又称为“四六风”“七日风”或“脐风”[1]。NT是严重威胁新生儿生 Neonatal tetanus (Neonatal tetanus, NT) is immigrant off the umbilical, lax disinfection, causing tetanus bacteria through the umbilical into the body, spasm toxin can be generated along lymphatic fluid, nerve stems and other spread to the spinal cord and brain stem, and the central Ganglioside binding in nerve tissue so that the latter can not release inhibitory nerve mediators, causing an acute infectious disease [1], in which the trismus closes and the body muscles strongly continue to contract. Usually 4 to 7 days after birth disease, it is also known as the “four winds” “seven wind ” or “umbilical wind ” [1]. NT is a serious threat to newborns