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对462例破伤风病人的临床资料进行分析表明,影响破伤风病人预后的因素主要是:①年龄:新生儿及老年病人病死率高达48.4%,而其它年龄组仅为18.4%,P<0.001;②潜伏期:潜伏期越短,病死率越高,潜伏期<9天的病人,病死率为54.5%,而>9天者仅为5.6%,P<0.001;③起病期(即首次抽搐到全身性痉挛所历时间):起病期越短,病死率越高。起病期<48小时者,病死率高达79.0%,而起病期>48小时者,病死率仅为19.2%,P<0.001;④痉挛的程度,如为反射性痉挛致发甜,甚至呼吸停止者,预后差,病死率为60.2%,而其它仅为10.8%,P<0.001。其它的原因还有自律性神经功能失调,并发其它感染,治疗不当等。
Analysis of 462 cases of tetanus clinical data showed that the main factors affecting the prognosis of patients with tetanus: ① age: neonatal and elderly patients mortality as high as 48.4%, while other age groups was only 18.4% , P <0.001; ② incubation period: the shorter the incubation period, the higher the mortality, the incubation period of <9 days of patients, the mortality rate was 54.5%, and> 9 days were only 5.6%, P < 001; ③ period of onset (that is, the first convulsions to systemic spastic experience of time): the shorter the onset period, the higher mortality. The onset period of <48 hours, the fatality rate as high as 79.0%, and the onset period of> 48 hours, the mortality rate was only 19.2%, P <0.001; ④ degree of spasticity, such as reflex spasms Induced to sweet, and even stopped breathing, the prognosis is poor, the case fatality rate was 60.2%, while the others were only 10.8%, P <0.001. Other reasons are self-discipline neurological disorders, complicated by other infections, improper treatment and so on.