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目的:探索肺炎支原体肺炎病程中D-二聚体、脂蛋白a (Lp (a) ) 的变化及临床意义。方法:采集病例组和健康对照组晨空腹血,测定D-二聚体、Lp (a) 。运用SPSS20.0分析所得数据。结果:病例组和对照组各40例。病例组D-二聚体及Lp (a) 均明显高于对照组(P<0.001)。未使用糖皮质激素(GC)的患儿D-二聚体有明显下降(P<0.05)。无论是否使用GC,Lp (a) 在恢复期均比急性期明显下降(P<0.001),且使用GC组下降得更加明显。结论:MPP感染后可存在长时间的高凝状态,在随访中应注重凝血功能的复查和监测。Lp (a) 可能成为一个衡量MP感染和凝血状态的新的指标。
Objective: To explore the changes and clinical significance of D-dimer and Lp (a) in the course of mycoplasma pneumoniae pneumonia. Methods: Morning fasting blood samples were collected from patients and healthy controls. D-dimer and Lp (a) were determined. Using SPSS20.0 analysis of the data. Results: The case group and the control group of 40 cases. D-dimer and Lp (a) in case group were significantly higher than those in control group (P <0.001). There was a significant decrease in D-dimer in children without glucocorticoid (GC) (P <0.05). Lp (a) was significantly lower than that in acute phase (P <0.001) during recovery and GC-treated group, with or without GC. Conclusion: MPP infection may exist for a long time hypercoagulable state, follow-up should focus on review and monitoring of coagulation. Lp (a) may be a new measure of MP infection and coagulation status.