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Duffy抗原,是Cutbush在1950年发现一名叫Duffy的输血后产生了溶血反应患者,在该患者血浆中发现了抗Fya抗体,之后确认了Fya抗原的存在。到1993年,确认了Fy基因的位点。1991年Daybomme等证实了Duffy抗原是红细胞膜上CC家族和CXC家族趋化因子的杂项趋化因子的受体,是红细胞上的趋化因子受体,也称为达菲抗原/趋化因子受体(Duffy.Antigen/Receptor for Chemokines,DARC)2010年,国际输血协会(ISBT)确
The Duffy antigen was discovered by Cutbush in 1950 when he was found to have hemolysis after a transfusion called Duffy, in which anti-Fya antibody was found in the plasma and then the presence of Fya antigen was confirmed. By 1993, the site of the Fy gene was confirmed. 1991 Daybomme et al. Confirmed that the Duffy antigen is a receptor for miscellaneous chemokines of the CC family and CXC family chemokines on erythrocyte membranes and is a chemokine receptor on erythrocytes, also known as Tamiflu antigen / chemokine receptor Body (Duffy.Antigen / Receptor for Chemokines, DARC) In 2010, the International Society of Blood Transfusion (ISBT)