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69例T2DM患者在降糖、活血等基础上随机分治疗组35例,加维奥欣480mg,3次/日,口服。对照组34例原治疗不变。共观察2年。记录患者自觉症状,血流变,血脂,双侧颈总、椎动脉内膜厚度及颅内各血管的血流速度、搏动指数等指标。结果治疗组症状及上述指标改善均优于对照组(P<0.05)。未发现明显毒副作用。结论维奥欣可延缓糖尿病患者动脉粥样硬化的进程,能改善大脑血流。
Sixty-nine patients with T2DM were randomly divided into treatment group (n = 35) and Gaviotin (n = 480) for 3 times daily on the basis of hypoglycemic and blood-activating. Control group, 34 cases of the original treatment unchanged. A total of 2 years of observation. Record patients with symptoms, blood rheology, blood lipids, bilateral total neck, vertebral artery intima thickness and intracranial blood flow velocity, pulsatility index and other indicators. Results The symptoms of the treatment group and the improvement of the above indexes were better than the control group (P <0.05). No significant side effects were found. Conclusions Vioxxhen can delay the process of atherosclerosis in diabetic patients and improve cerebral blood flow.