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目的:运用Meta分析的方法,科学评价Gluma脱敏剂对牙本质过敏症的临床疗效,指导临床治疗。方法:检索中国生物医学文献数据库和Ovid medline数据库中关于Gluma脱敏剂和75%氟化钠甘油对牙本质过敏症治疗研究的文献,通过纳入和排除标准筛选文献,评价文献质量,提取数据,并进行Meta分析。结果:7个试验研究共1898颗牙齿纳入分析,合并RR值为1.51,95%可信区间为[1.44～1.59],合并效应检验值Z=15.68,P<0.00001。结论:表明Gluma脱敏剂治疗牙本质过敏症效果优于75%氟化钠甘油。
Objective: To evaluate the clinical effect of Gluma desensitizer on dentine hypersensitivity by means of Meta analysis and to guide the clinical treatment. METHODS: The literature on the treatment of dentin hypersensitivity by Gluma desensitizer and 75% sodium fluoride glycerol in the Chinese Biomedical Literature Database and the Ovid medline database was searched. The literatures were screened out by inclusion and exclusion criteria, the quality of the literature was evaluated, the data were extracted, Meta-analysis was performed. Results: A total of 1898 teeth were included in the 7 trials. The combined RR was 1.51, the 95% confidence interval was [1.44-1.59], and the combined effect test was Z = 15.68, P <0.00001. CONCLUSIONS: Gluma desensitizers are superior to 75% sodium fluoride glycerol in the treatment of dentin hypersensitivity.