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目的 :总结肺癌患者多原发恶性肿瘤的诊断和治疗经验。方法 :分析肺癌患者多原发恶性肿瘤 45例的临床病理资料 ,占同期手术病理证实 1836例肺癌的 2 .5 %。男 38例 ,女 7例。多原发肺癌 16例 ,占 0 .9% ,其中15例为双原发癌 ,1例为三原发癌 ;肺癌与其他脏器恶性肿瘤 2 9例 ,占 1.6 % ,其中 2 7例为双原发恶性肿瘤 ,2例为三原发癌。结果 :多原发肺癌患者术后 3和 5年生存率为 6 0 .0 % (6 /10 )和 44 .4% (4 /9) ;发生在肺癌前的其他脏器恶性肿瘤患者 ,肺癌切除术后 3～ 5年生存率为 6 9.2 % (9/13)和 36 .4% (4 /11)。手术疗效明显高于非手术治疗组。结论 :随着医学的发展 ,医患对多原发癌认识的不断增强 ,其早期诊断及检出率的不断提高 ,并采取积极的手术治疗 ,将会使多原发癌患者获得更加理想的疗效。
Objective: To summarize the diagnosis and treatment experience of multiple primary malignant tumors in patients with lung cancer. Methods : To analyze the clinicopathological data of 45 patients with primary malignant tumors of lung cancer, accounting for 2.5 % of 1836 lung cancers confirmed by pathology at the same period. There were 38 males and 7 females. There were 16 primary lung cancers, accounting for 0.9%, of which 15 were dual primary cancers, and 1 was tri-primary cancer. Lung cancer and other organ malignant tumors were 29, accounting for 1.6%, of which 27 were Two primary malignancies, two cases of primary cancer. RESULTS: The 3-year and 5-year survival rates of patients with multiple primary lung cancer were 60.0% (6/10) and 44.4% (4/9) postoperatively; lung cancers occurred in other organs with lung cancer before lung cancer. The 3- to 5-year survival rate after resection was 6 9.2% (9/13) and 36.4% (4/11). The surgical effect was significantly higher than the non-surgical treatment group. Conclusion: With the development of medicine, doctors and patients are increasingly aware of multiple primary cancers, their early diagnosis and detection rate are increasing, and active surgical treatment will make multi-primary cancer patients more ideal Efficacy.