[目的]了解北京、广州两地女性乳腺癌的发病水平,筛选危险因素。[方法]于2006年到2007期间问卷调查了2223人,其中乳腺癌病人729例,对照1494例,分析调查所得资料。[结果]妇女罹患乳腺癌的可能危险因素中影响较突出的是:有绝经史、有流产史、有药物避孕史、有乳腺癌家族史、不良情绪、不良事件、情绪调节能力差、劳动强度大、年龄。[结论]乳腺癌重在预防,应结合其危险因素开展积极有效的防治措施 [Objective] To understand the incidence of breast cancer in Beijing and Guangzhou and to screen risk factors. [Method] During the period from 2006 to 2007, 2223 people were surveyed, including 729 breast cancer patients and 1494 controls. The data of the survey were analyzed. [Results] Among the possible risk factors of breast cancer in women, the most prominent ones were menopausal history, history of abortion, history of drug contraception, family history of breast cancer, adverse emotions, adverse events, poor emotion regulation, labor intensity Big, age [Conclusion] Breast cancer focuses on prevention, and active and effective prevention and control measures should be carried out in combination with its risk factors