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目的:本文对36例肝硬化患者采用99mTCEHIDA(二乙基丁酰苯胺基亚氨二醋酸)进行肝脏动态显像检查,并作定量分析,以便对肝硬化患者的贮备功能作出正确估价。方法:每位患者在检查前禁食4小时以上,检查时仰卧于r相同探头下,静注88mTCEHIDAF40MBg,前位连续功态采集每一帧/60秒,连续采集30分钟,60分钟再作静态采集一帧,经计算机处理手作定量分析。结果:结果表明肝硬化者血液中清除指数(H5/H2min)、心肝比值(H5/L5min)均较对照组明显增大,而30分钟排泄率则较对照组为低(EX30min)、两组核素显像定量值相比均有显著差异(P<0.01),且与肝硬心病情程度相关,按childPngh分期,A、B、C级之间H5/H2min、H5/L5min、E×30min核素定量结果互相对比均有显著差异(P<0.05~0.01)。上述三项参数与肝功能实验检测指标间有一定相关性。结论:本组资料提示该方法较敏感反映肝硬化不同时期的贮备功能,对肝硬化的早期诊断等有一定的临床价值。
Objective: In this paper, 36 patients with liver cirrhosis using 99mTC EIDID (diethyl butyryl anilino iminodiacetic acid) for liver dynamic imaging examination, and for quantitative analysis, in order to make a correct assessment of patients with cirrhosis of the reserve function. Methods: Each patient was fasted for more than 4 hours before the test. At the time of examination, they were supine on the same probe. The 88mTCEHIDAF40MBg was injected intravenously. The first continuous acquisition of each frame / 60s, continuous acquisition for 30 minutes and 60 minutes For static acquisition of a frame, by computer processing for quantitative analysis. Results: The levels of H5 / H2min and H5 / L5min in cirrhotic patients were significantly higher than those in control group, while the excretion rate in 30 minutes was lower than that in control group (EX30min) (P <0.01), and with the severity of cirrhosis, according to child Pngh staging, H5 / H2min, H5 / L5min between A, B and C levels, E × 30min nuclide quantitative results were significantly different from each other (P <0.05 ~ 0.01). The above three parameters and liver function tests have some correlation between indicators. Conclusion: The data suggest that this method is more sensitive to reflect the different stages of cirrhosis of the reserve function of cirrhosis of the early diagnosis of a certain clinical value.