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目的:本研究观察大剂量胸腺肽对恶性肿瘤介入化疗病人T细胞亚群的影响。方法:分介入化疗加胸腺肽组(实验组)和单纯介入化疗组(对照组),实验组于介入化疗同时每日静点胸腺肽50~100mg,连续10~14天后检测T淋巴细胞亚群的变化。结果:实验组介入化疗后CD_3、CD_4和NK阳性百分率及CD_4/CD_8比值均明显高于本组介入化疗前和对照组介入化疗后水平。结论:大剂量胸腺肽可在短时间内提高恶性肿瘤介入化疗病人机体的免疫功能。
Objective: This study was to observe the effects of high dose thymosin on T cell subsets in patients with malignant tumor after interventional chemotherapy. Methods: The interventional chemotherapy combined with thymosin (experimental group) and chemotherapy alone group (control group), the experimental group in the interventional chemotherapy at the same time daily static point thymosin 50 ~ 100mg, continuous 10 ~ 14 days after T lymphocyte subsets were detected . Results: The positive percentage of CD_3, CD_4 and NK and the ratio of CD_4 / CD_8 after interventional chemotherapy in the experimental group were significantly higher than those before and after the intervention in the control group. Conclusion: High-dose thymosin can improve the immune function of patients with malignant tumor interventional chemotherapy in a short period of time.