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目前一般认为间歇性干咳是ACE抑制剂的主要副作用之一,临床常可导致病人中断治疗。作者研究了这一副作用的发生率,并对其临床意义作了评估。试验对连续使用ACE抑制剂达1年以上的164例高血压患者和104例充血性心衰患者,作了药物引起咳嗽和其它副作用的前瞻性研究。试验中每4
It is generally believed that intermittent dry cough is one of the major side effects of ACE inhibitors, which can often lead to discontinuation of treatment in the clinic. The authors studied the incidence of this side effect and evaluated its clinical significance. The trial prospectively studied drug-induced cough and other adverse events in 164 hypertensive patients and 104 patients with congestive heart failure who had been using ACE inhibitors for more than 1 year. Every 4