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本期 BMJ 刊登了 Walter 及其同事的一篇抗甲状腺药物对放射性碘治疗影响的随机对照试验的系统性综述和荟萃分析(见第216页)。放射性碘被认为是使用简便和性价比较好的治疗甲状腺功能亢进(甲亢)的方法。β肾上腺素能受体阻断剂,如普萘洛尔(每日总量80～160mg),通常能在首诊至放射性碘治疗的期间明显减轻患者症状,随后6～8周,直至治疗有效。对于老年患者和严重甲亢或有心血管并发症患者,例如心房纤颤和心力衰竭,通常的做法是首先采用抗甲状腺药物治疗,使甲状腺功能恢复正常。这
This issue of the BMJ publishes a systematic review and meta-analysis of a randomized controlled trial of anti-thyroid drugs on the effects of radioiodine treatment by Walter and colleagues (see page 216). Radioactive iodine is considered to be a simple and cost-effective method for the treatment of hyperthyroidism (hyperthyroidism). Beta-adrenergic receptor blockers, such as propranolol (80-160 mg total daily), usually reduce symptoms significantly during the first visit to radioactive iodine therapy, and then continue for 6-8 weeks until effective . For elderly patients and patients with severe hyperthyroidism or cardiovascular complications, such as atrial fibrillation and heart failure, the usual practice is to first use anti-thyroid drugs to restore normal thyroid function. This