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AIM To compare the tolerability and quality of bowel cleansing between 2 L polyethylene glycol(PEG)and reduced-dose sodium phosphate(Na P)tablets as a preparation for colonoscopy.METHODS Two hundred patients were randomly assigned to the PEG or Na P groups at the same ratio.The Na P group patients took 30 tablets with 2 L of clear liquid,while the PEG group patients took 2L of PEG.Tolerability was assessed by a questionnaire about taste,volume,and the overall impression.The bowel cleansing quality was evaluated by colonoscopists.RESULTS Although Na P showed better tolerability in terms of taste,volume and overall impression(P<0.01,P<0.01 and P=0.02,respectively),the overall cleansing quality was better in the PEG group(P<0.01).A subgroup analysis,stratified by sex and age,indicated that Na P was associated with better tolerability and equivalent bowel cleansing quality in females of<50years of age.CONCLUSION Despite the better tolerability,the use of 30 Na P tablets with 2 L of clear liquid should be limited due to its lower cleansing quality;however,in certain cases the regimen may deserve consideration,particularly in cases involving young women.
AIM To compare the tolerability and quality of bowel cleansing between 2 L polyethylene glycol (PEG) and reduced-dose sodium phosphate (Na P) tablets as a preparation for colonoscopy. METHODS Two hundred patients were randomly assigned to the PEG or Na P groups at the same ratio.The Na P group patients took 30 tablets with 2 L of clear liquid, while the PEG group patients took 2L of PEG.Tolerability was assessed by a questionnaire about taste, volume, and the overall impression. the bowel cleansing quality was evaluated by colonoscopists. Although Na P showed better tolerability in terms of taste, volume and overall impression (P <0.01, P <0.01 and P = 0.02, respectively), the overall cleansing quality was better in the PEG group A subgroup analysis, stratified by sex and age, that that Na P was associated with better tolerability and equivalent bowel cleansing quality in females of <50 years of age. CONCLUSION Despite the better tolerability, the use of 30 Na P tablets with 2 L of clear l iquid should be limited due to its lower cleansing quality; however, in certain cases the regimen may deserve consideration, particularly in cases involving young women.