多发性骨髓瘤(multiple myeloma,MM)是浆细胞异常增生的恶性肿瘤,男性多于女性,中老年占多数,其发病率约为2～3/10万人口,因MM的临床表现具有多形性特点。病人常被以不同疾病名称收治或病死于各科,应引起临床医生警惕。骨痛是MM最常见的症状,并可为早期和主要的症状。早期骨痛可较轻,可为游走性或间歇性,后 Multiple myeloma (MM) is a malignant tumor of plasma cell dysplasia, more men than women, the majority of middle-aged and elderly, the incidence of about 2 to 3/10 million population, due to the clinical manifestations of MM with polymorphism Sexual characteristics. Patients are often treated with different disease names or died in various subjects, should cause clinicians vigilance. Bone pain is the most common symptom of MM and can be an early and major symptom. Early bone pain can be lighter, can be migratory or intermittent, after