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肝纤维化是临床慢性肝病常见的病理改变,是慢性肝炎向肝硬化发展的必经之路。食管静脉曲张破裂出血是肝硬化的严重并发症之一,约占上消化道出血的50％～80％,位居首位。近年研究表明,血清层粘连蛋白(LN)水平与肝硬化的发生、发展有密切关系,尤其是与食管静脉曲张程度的关系越来越引起人们的关注。本文就108例肝炎后肝硬化病例LN水平与食管静脉曲张程度的关系作一分析。 材料和方法 1 研究对象 1997年1月至1998年7月本院传染科连续住院的肝炎后肝硬化患者108例,男91例,女17例,年龄43.75±16.92岁,所有病例均测定血清LN水平,同时行电子胃镜检
Liver fibrosis is a common pathological change in clinical chronic liver disease, is the only way for the development of chronic hepatitis to cirrhosis. Esophageal variceal bleeding is a serious complication of cirrhosis, accounting for about 50% to 80% of upper gastrointestinal bleeding, ranking first place. In recent years, studies have shown that serum laminin (LN) levels and the occurrence and development of cirrhosis are closely related, especially with the esophageal varicose degree more and more cause for concern. In this paper, 108 cases of posthepatitic cirrhosis cases LN level and the relationship between esophageal varices for an analysis. Materials and Methods 1 Subjects: From January 1997 to July 1998, 108 consecutive patients with posthepatitic cirrhosis who were admitted to Department of Infectious Diseases in our hospital, including 91 males and 17 females, aged 43.75 ± 16.92 years. Serum levels of LN Level, while electronic gastroscopy