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原发性中枢神经系统非何杰金氏淋巴瘤(PCNSL)指疾病限于脑-脊髓轴而无全身受侵的淋巴瘤,属罕见病。作者对1982～1994年Peter Mac-Callum Cancer Institute(PMCI)收治的62例PCNSL患者的回顾性研究,探讨PCNSL的治疗手段及预后因素。 62例中男性33例,女性29例,年龄6～87岁,WHO一般状况评分≥2者占85％(53/62)。均经活检证实,无HIV感染证据,均行头颅CT检查,92％进行了骨髓活检,60％(37/62)进行了脑脊液检查。 所有患者均接受激素治疗及全脑放疗。全脑放
Primary central nervous system non-Hodgkin’s lymphoma (PCNSL) refers to the disease limited to the brain - spinal axis without systemic invasion of lymphoma, is a rare disease. The authors retrospectively reviewed 62 PCNSL patients enrolled in the Peter Mac-Callum Cancer Institute (PMCI) from 1982 to 1994 to investigate the treatment and prognostic factors of PCNSL. Of the 62 patients, 33 were male and 29 were female, with a mean age of 6 to 87 years and 85% (53/62) with a WHO general condition score ≥2. All were confirmed by biopsy and had no evidence of HIV infection. All patients underwent cranial CT examination, bone marrow biopsy was performed in 92%, and cerebrospinal fluid was examined in 60% (37/62). All patients received hormone therapy and whole-brain radiotherapy. Whole brain release