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对３００例服用米非司酮伍用米索前列醇抗早孕的妇女进行临床效果观察。其完全流产率为９１％，不全流产率为２．７％，失败率为６．３％。主要副反应为轻微呕吐、腹泻及腹痛。现主要存在问题为阴道流血时间长，平均出血天数为１２．８５ｄ，自述出血量超过自身月经量１倍者占２２％，及时施行刮宫术可有效地缩短出血时间。１５例再次使用此方法终止早孕者其疗效均与首次相同。结论：此方法抗早孕有效、安全、简便，对高危患者尤为适用。
Clinical efficacy of 300 women taking mifepristone and misoprostol for anti-early pregnancy was observed. The complete abortion rate was 91%, incomplete abortion rate was 2.7%, the failure rate was 6.3%. The main side effects are mild vomiting, diarrhea and abdominal pain. The main problems are the vaginal bleeding for a long time, the average number of bleeding days 12.85d, self-reported bleeding more than 1 times their own menstrual flow accounted for 22%, timely implementation of curettage can effectively shorten the bleeding time. 15 cases of re-use of this method to terminate pregnancy are the same as the first time their efficacy. Conclusion: This method is effective, safe and easy for early pregnancy, especially for high-risk patients.