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研究表明 ,肠源性介质与多器官功能障碍综合征的发病及内皮细胞损害有关。最近 ,Osband等对其相关细胞途径进行了研究 ,他们搜集了创伤失血性休克后 1～ 3h大鼠肠系膜淋巴液 ,并测定了该淋巴液对人脐静脉内皮细胞 (HUVECs)的毒性作用。同时他们应用 30余种药物抑制创伤失血性休
Studies have shown that gut-derived mediators are associated with multiple organ dysfunction syndrome and endothelial cell damage. Recently, Osband et al. Studied the relevant cellular pathways. They collected rat mesenteric lymphocytes 1 to 3 hours after traumatic hemorrhagic shock and determined the toxic effects of the lymph on human umbilical vein endothelial cells (HUVECs). At the same time they use more than 30 kinds of drugs to inhibit traumatic hemorrhagic Hugh