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经胎盘传播IgG抗体而致新生儿同种免疫性中性粒细胞减少症较为罕见,它是由母亲抗人中性粒细胞抗原(HNA)-1b抗体引起的,可合并感染,粒细胞集落刺激因子(G-CSF)治疗有效。本文报道1例由输血引起的严重而持续的新生儿中性粒细胞减少症。
Neonatal alloimmune neutropenia caused by placental transmission of IgG antibodies is rare and is caused by maternal anti-human neutrophil antigen (HNA) -1b antibody, which can be combined with infection, granulocyte colony stimulation Factor (G-CSF) treatment is effective. This article reports a severe and persistent neonatal neutropenia caused by blood transfusions.