《内科新说》下卷为合信、管茂材同撰,刊行于1858年,是目前所知最早系统介绍西方药学的著作。本文概述该书的药学内容、对“药剂”的介绍、对药品的介绍等,并指出该书对我国中医中药的偏颇看法以及多方面宣扬西方文化与医药等情况。 The new book “Internal Medicine” was written by He Xin, Guan Maocai, and published in 1858. It is the earliest known introduction to western pharmacy. This article gives an overview of the book’s pharmaceutical content, introduction to “Pharmaceuticals,” and introductions to medicines. It also points out the book’s biased views on Chinese medicine in China and the promotion of Western culture and medicine in many aspects.