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目的为了解我市中小学生抗-HBS阳性率及乙型肝炎(乙肝)病毒(HBV)感染情况为制定乙肝防制计划提供科学依据。方法在白城市区内1988～1997年出生的中小学生为对象,随机抽取10082名,采静脉血,用酶联免疫吸附试验(ELISA)法检测抗-HBS及HBV感染指标。结果有35.83%(3612/10082)的中小学生乙肝保护性抗体(抗-HBS≥10mIU/ml)阳性。有64.17%(6470/10082)的中小学生抗-HBS阴性或低滴度(<10mIU/ml)。有1.28%(129/10082)的中小学生检测到不同程度的HBV感染,男女性别间差别有显著意义。结论建议把抗-HBS阴性的中小学生全程注射乙肝疫苗,抗-HBS低滴度中小学生加强免疫乙肝疫苗。
Objective To understand the positive rate of anti-HBs and the hepatitis B virus (HBV) infection of primary and secondary students in our city to provide a scientific basis for the development of hepatitis B prevention and control plan. Methods Primary and secondary pupils born in 1988 ~ 1997 in Baicheng city were enrolled in this study. 10082 randomly selected venous blood samples were collected for detection of anti-HBS and HBV infection by enzyme-linked immunosorbent assay (ELISA). Results 35.83% (3612/10082) of primary and secondary hepatitis B protective antibodies (anti-HBS ≥ 10mIU / ml) positive. There were 64.17% (6470/10082) of primary and secondary students anti-HBS negative or low titer (<10mIU / ml). There were 1.28% (129/10082) of primary and secondary students detected different degrees of HBV infection, gender differences between men and women have significant significance. Conclusions It is suggested that hepatitis B vaccine should be injected into primary and secondary school students with anti-HBS negative and anti-HBs low titers should be strengthened to immunize hepatitis B vaccine.