本文应用色氨酸耐量试验检测118例病理确诊的慢性肝病及77例对照者的肝功能,显示其对慢性迁延性肝炎的检出率96.6%,慢性活动性肝炎95.5%,肝硬化100%;统计敏感度90.6%,特异度92.2%,阳性预测值94.6%,阴性预测值86.5%,准确率91.2%。55例患者自身对照证实本试验敏感度优于吲哚氰绿、血清胆酸和常规肝功能试验。受试者无不良反应,建议临床试用。 In this paper, 118 patients with pathologically diagnosed chronic liver disease and 77 controls were tested for their liver function by tryptophan tolerance test. The results showed that the detection rate was 96.6% for chronic persistent hepatitis, 95.5% for chronic active hepatitis and 100% for cirrhosis. Statistical sensitivity was 90.6%, specificity was 92.2%, positive predictive value was 94.6%, negative predictive value was 86.5%, and accuracy rate was 91.2%. 55 patients with their own control confirmed that the sensitivity of this test is better than indocyanine green, serum bile acids and conventional liver function tests. Subjects without adverse reactions, it is recommended clinical trial.