纤维连接素(Fibronectin,Fn)是一组具有广泛生物学活性的糖蛋白,主要分为血浆型和细胞型两种。血浆型Fn是可溶性的,主要分布在血液内,参于血液凝固,促进调理吞噬(故又称调理素)。细胞型Fn是不溶性的,主要分布在细胞表面和细胞外基质内,具有促进细胞与细胞、细胞与基质的粘连,维持细胞形态,促进细胞分化、移动,参于趋化反应。血浆型Fn可以渗到组织中,在因子XⅢa的作用下,转变成细胞型Fn。近几年,有关Fn的基础研究取 Fibronectin (Fn) is a group of glycoproteins with a wide range of biological activities, which are mainly divided into plasma type and cell type. Plasma Fn is soluble, mainly distributed in the blood, the reference to blood coagulation, promote conditioning phagocytosis (also known as opsonin). Cell type Fn is insoluble, mainly distributed in the cell surface and extracellular matrix, with the promotion of cells and cells, cells and matrix adhesion, maintain cell morphology, promote cell differentiation, migration, participation in chemotactic response. Fn plasma can penetrate into the tissue, in the role of factor XIIIa, into a cell type Fn. In recent years, basic research on Fn taken