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将50例老年慢性阻塞性肺病(COPD)和肺心病院内感染患者随机分为两组,分别用环丙氟哌酸(CIP)和头孢哌酮(CPZ)治疗,观察症状、体征、胸片、痰细菌培养尿N—乙酰—β—D—氨基葡萄糖苷酶(NAG)等.结果:总有效率CIP组为87.5%,CPZ组为88.5%,两组疗效均好且相近;但CIP组的二重感染和尿NAG增高少于CPZ组(P<0.05),且CIP价格相对低廉.提示:治疗老年COPD和肺心病院内感染时选用CIP较为可取.
Fifty patients with chronic obstructive pulmonary disease (COPD) and pulmonary heart disease (nosocomial infection) were randomly divided into two groups. The patients were treated with Ciprofloxacin (CIP) and cefoperazone (CPZ) respectively. The symptoms, signs, Sputum bacterial culture urine N-acetyl-β-D-glucosaminidase (NAG), etc. Results: The total effective rate of CIP group was 87.5%, CPZ group was 88.5%, both groups were good and similar efficacy; Double infection and urinary NAG increased less than the CPZ group (P <0.05), and the CIP price is relatively low.It is suggested that the treatment of elderly COPD and pulmonary heart disease in the selection of CIP is preferable.