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目的：探讨妊高征与红细胞膜胆固醇及磷脂含量的关系。方法：采用比色法及全自动生化分析仪对２４例健康未孕妇女，２２例正常妊娠妇女及３６例妊高征患者进行了红细胞膜胆固醇及磷脂含量的测定。结果：中、重度妊高征组红细胞膜胆固醇含量明显高于其他各组（Ｐ＜００１）；轻度妊高征组膜胆固醇含量与正常妊娠组间无显著差异（Ｐ＞００５）；各组间红细胞膜磷脂含量差异无显著性（Ｐ＞００５）。结论：红细胞膜胆固醇含量升高参与了妊高征的病理生理过程。
Objective: To investigate the relationship between pregnancy-induced hypertension and erythrocyte membrane cholesterol and phospholipid content. Methods: The content of erythrocyte membrane cholesterol and phospholipid in 24 healthy pregnant women, 22 normal pregnant women and 36 patients with PIH were measured by colorimetric method and automatic biochemical analyzer. Results: The contents of erythrocyte membrane cholesterol in moderate and severe PIH group were significantly higher than those in other groups (P <001). There was no significant difference in the levels of serum cholesterol between mild PIH group and normal pregnancy group (P> 0.05) ). There was no significant difference in erythrocyte membrane phospholipid content between groups (P> 005). Conclusion: Elevated erythrocyte membrane cholesterol is involved in the pathophysiological process of PIH.