论文部分内容阅读
肿瘤血管形成在实体瘤的发生、发展、转移及预后中起着重要作用，对指导治疗也有深远的影响。通过对大肠癌组织内微血管的定量计数，发现微血管计数与大肠癌病人的转移和生存率有明显相关性，是一个有价值的独立的预后因素。认为大肠癌组织内微血管的定量计数可反映肿瘤血管生成情况，在判断肿瘤预后，筛选高危复发或转移病人，指导治疗等方面有较大应用价值。本文综述了大肠癌组织内微血管定量的方法、微血管计数与大肠癌转移和预后的关系及意义。
Tumor angiogenesis plays an important role in the occurrence, development, metastasis, and prognosis of solid tumors, and it also has a profound impact on guiding treatment. Through the quantitative counting of microvessels in colorectal cancer tissues, it is found that microvessel counts are significantly correlated with the metastasis and survival rate of colorectal cancer patients, and it is a valuable independent prognostic factor. It is believed that the quantitative counting of microvessels in colorectal cancer tissue can reflect the angiogenesis of tumors, and has great application value in judging the prognosis of cancer, screening high-risk relapsed or metastatic patients, and guiding treatment. This article reviews the methods of microvessel quantification in colorectal cancer, the relationship between microvessel counts and the metastasis and prognosis of colorectal cancer.