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本文对一组印度妇女用低剂量复合型OC(乙炔雌二醇30μg+消旋18-甲基炔诺酮500μg)12个月于用药前及用药后3、6、12个月对糖代谢的影响进行研究。月经规则,无糖尿病家族史和隐性糖尿病史(分娩巨大儿及肥胖妇女)的20例20～30岁妇女,经全面体检和妇科检查正常,受试前未用甾体避孕药,受试期间不用影响糖代谢的其他药物。受试前3天吃高碳水化合物饮食,于周期第3周末前晚禁食,次晨作口服葡萄糖耐量试验(OGTT),口服葡萄糖1 g/kg体重,于服糖前及后1、2、3小时取血样,血清分成2份,1份立即用Dubowsk法测血糖,另1份贮于-20℃,用于RIA测胰岛素水平。服OC后3、6、12个月重复作OGTT。
In this paper, a group of Indian women with low-dose compound OC (ethinyl estradiol 30μg + racemic 18-norgestrel 500μg) 12 months before and 3,6,6 months after administration of sugar metabolism research. Menstruation rules, a family history of diabetes and a history of recessive diabetes (childbirth giant and obese women) 20 20 to 30-year-old women, after a comprehensive physical examination and gynecological examination were normal, before the test without steroid contraceptives, during the test period No other drugs that affect glucose metabolism. The high carbohydrate diet was eaten 3 days before the test, and fasting was performed on the 3rd weekend before the end of the week. Oral glucose tolerance test (OGTT) and oral glucose 1 g / kg body weight were performed on the morning of the third week, Blood samples were taken at 3 hours, serum was divided into 2 portions, 1 portion was immediately tested for blood sugar with Dubowsk method, and 1 portion was stored at -20 ° C for RIA insulin levels. OCG 3,6,12 months after repeated OGTT.