肿瘤的机械阻力和标准疗法的附带损伤往往会阻碍抵御癌症的效果,近日,来自法国国家健康与医学研究所等机构的研究人员通过对肿瘤加热成功软化了恶性肿瘤,这种方法称之为纳米热疗法,其能够让肿瘤对治疗制剂更加敏感,相关研究刊登于国际杂志Theranostics上。研究者首先将碳纳米管(CNTs)直接注入到肿瘤中,随后利用激光辐射来激活纳米管,与此同时肿瘤周围的健康组织并不会受到损伤。如今研究人员越来越关注影响肿瘤发展的机械因素,肿瘤变硬主要是因为胶原纤维和细胞外基质的 Tumor mechanical resistance and incidental damage to standard therapy tend to hinder the fight against cancer. Researchers from the French National Institute of Health and Medicine have recently softened malignant tumors by heating tumors, a technique known as nanotechnology Thermotherapy, which enables tumors to be more sensitive to therapeutic agents, has been published in the journal Theranostics. The researchers first injected carbon nanotubes (CNTs) directly into the tumor and then used laser radiation to activate the nanotube, while at the same time healthy tissue surrounding the tumor was not damaged. Now researchers are paying more and more attention to the mechanical factors that affect the development of tumors. The harden of tumors is mainly due to the collagen fibers and extracellular matrix