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在ＢＡＬＢ／ｃ小鼠生产群中，１罐（：＝１：１交配）繁殖鼠生下２ ．７被毛稀疏的仔鼠。该对仔鼠成年后进行兄妹交配，后代出现三种表型：被毛紧披，生长快，繁殖力强的正常全毛小鼠；完全无毛，有胸腺，生长慢，性成熟晚，雄性隐睾率高，雌性窝产仔数少的无毛鼠；被毛稀疏，生长较快，繁殖率较高的中间态稀毛鼠。三种小鼠皆能在开放系统中生存，寿命 １．５～２年。对这些小鼠进行交配试验，结果表明：此种突变由位于常染色体上的单对基因控制，呈半显性。三种表型小鼠的基因型为全毛＋／＋、无毛 ｂ／ｂ、稀毛 ｂ／＋。该突变既影响小鼠的上皮组织，又影响小鼠的繁殖、生长等性能。该小鼠可望成为皮肤、免疫、化妆品等研究领域的动物模型。
In the BALB / c mouse production group, 1 canine (= 1: 1 mating) breeding mouse was born 2. 7 hairless sparse pups. The offspring mating siblings adult, offspring there are three phenotypes: tight tucked hair, fast growth, strong reproductive capacity of normal hairy mice; completely glabrous, thymus, slow growth, late sexual maturity, male The rate of cryptorchidism is high, the number of litters in the litter of females is less than that in the middle females with sparse hair, rapid growth and high reproduction rate. Three kinds of mice are able to survive in an open system with a lifespan of 1.5-2 years. Mating experiments on these mice showed that the mutation was semi-dominantly controlled by a single pair of genes located on an autosomal chromosome. The genotypes of the three phenotype mice were total hair + / +, hairless b / b, hairy hair b / +. The mutation not only affects the mouse epithelial tissue, but also affect the mouse’s reproduction, growth and other properties. This mouse is expected to be an animal model for research in the fields of skin, immunity, cosmetics and the like.