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目的和方法：采用动态检测技术观察３１例皮质下动脉硬化性脑病和对照组３１例健康人血压和心率的变异性。结果：患者均存在动态血压异常，其中平均收缩压、平均舒张压超过正常值者２７例（８７％），夜间基底血压异常升高２２例（７１％），血压异常波动２０例（６４％），昼夜节律逆转４例（１３％）。患者心率变异时域指标２４小时内全部正常心动周期的标准差、２４小时内５分钟节段平均正常心动周期的标准差、在一定时间内相邻两正常心动周期差值大于５０毫秒的个数所占的百分比均明显低于对照组，收缩压与心率无显著相关性。结论：提示血压波动及持续的夜间升压现象在该病中起着一定作用，而这种异常可能与患者植物神经系统功能失调有关
PURPOSE AND METHODS: The dynamic changes of blood pressure and heart rate in 31 cases of subcortical arteriosclerotic encephalopathy and 31 healthy controls were observed by dynamic detection technique. Results: All the patients had ambulatory blood pressure abnormalities. Among them, 27 cases (87%) had mean systolic blood pressure and mean diastolic blood pressure more than normal, 22 cases (71%) had abnormal basal blood pressure abnormality at night, and 20 cases (64% , Circadian rhythm reversal in 4 cases (13%). Patient heart rate variability Time domain indicators Standard deviation of all normal cardiac cycles within 24 hours, standard deviation of average normal cardiac cycle in 5-minute segments within 24 hours, the number of adjacent two normal cardiac cycle differences greater than 50 milliseconds within a certain period of time The percentage was significantly lower than the control group, systolic blood pressure and heart rate was not significantly correlated. CONCLUSIONS: This suggests that fluctuations in blood pressure and persistent nocturnal boost may play a role in the disease, which may be related to dysfunction of the autonomic nervous system in patients