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目的 :探究侵袭性牙周炎患者淀粉样蛋白A、血浆钙结合蛋白与牙周探诊深度(PD)、出血指数(BI)及附着水平(AL)之间的相关性。方法 :分析2015年1月~2016年7月在我院接受治疗的41例广泛侵袭性牙周炎患者的临床资料,并列为观察组,选取46例牙齿健康人群作为对照组。结果 :观察组患者SSA、血浆钙结合蛋白水平明显高于对照组,差异具有统计学意义;观察组患者牙周探诊深度、出血指数及附着水平均高于对照组,差异具有统计学意义;采取Pearson相关性检验进行分析,观察组SSA、血浆钙结合蛋白与牙周探诊深度、出血指数及附着水平均呈正相关关系。结论 :侵袭性牙周炎发病可能与外周血SSA、血浆钙结合蛋白水平升高有关,对病情诊断和预后评价具有一定的临床价值
Objective: To investigate the correlation between amyloid A, plasma calcium binding protein and periodontal exploration depth (PD), hemorrhage index (BI) and attachment level (AL) in patients with aggressive periodontitis. Methods: The clinical data of 41 patients with extensive invasive periodontitis who were treated in our hospital from January 2015 to July 2016 were analyzed. The data of 46 patients with healthy teeth were selected as the control group. Results: The levels of SSA and plasma calcium-binding protein in the observation group were significantly higher than those in the control group, the difference was statistically significant. The exploration depth, hemorrhage index and adhesion level in the observation group were higher than those in the control group, the difference was statistically significant; Pearson correlation test was used to analyze the observation group, SSA, plasma calcium-binding protein and periodontal exploration depth, hemorrhage index and adhesion levels were positively correlated. Conclusion: The incidence of aggressive periodontitis may be related to the increase of peripheral blood SSA and plasma calcium-binding protein, and has certain clinical value in the diagnosis and prognosis evaluation