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研究目的:为了确定哮喘病人静脉注射硫酸鲜作为哮喘标准化治疗的一部分能否改善急诊科哮喘加重病人的肺功能和降低入院率.以随机化的双盲安慰剂对照研究,急性哮喘病人予β-受体兴奋剂吸入和静脉注射激素.在用药后30min给病人2g的硫酸镁静脉注射作为辅助治疗并以安慰剂(50mg生理盐水)静脉注射,监测静脉注射后的0、30、60、120、240 min内的肺功能,从急诊科转出的病人随访1～7d.哮喘病人135人;年龄18～65岁;男38人,女97人.
OBJECTIVES: In order to determine whether intravenous injection of sulphate in asthma as part of standardized treatment of asthma can improve asthma exacerbation in patients with emergency department and to reduce admission rate, a randomized, double-blind, placebo-controlled study of patients with acute asthma, Receptor agonist inhalation and intravenous injection of hormones to patients 2g 30mg intravenous injection of magnesium sulfate as adjuvant therapy and placebo (50mg saline) intravenous injection monitoring 0,30,60,120 after intravenous injection, Pulmonary function within 240 minutes followed up from 1 to 7 days in the emergency department. 135 asthmatic patients; aged 18-65 years; 38 males and 97 females.