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目的对血液恶性肿瘤患者化疗后口腔感染的相关危险因素进行分析和探究。方法选取我院2012-04-2015-04收治的接受化疗的血液恶性肿瘤患者74例为研究对象,利用多种方法对化疗结束后口腔感染发生的危险因素进行相关分析,同时提出相关预防措施。结果颊部和牙龈是口腔感染发生率较高的部位,口腔感染的发生率与患者大部分临床资料呈正相关关系,口腔感染发生的高风险因素主要有年龄、血清白蛋白水平在40g/L以下、粒细胞绝对值在0.5×109 L-1以下、口腔环境差、口腔自洁习惯差、多次化疗周期、化疗未缓解几种。结论血液恶性肿瘤患者进行化疗后导致口腔感染发生的因素有很多,必须采取针对性预防措施干预导致口腔感染发生的因素,减少口腔感染的发生,提升患者的生命质量。
Objective To analyze and explore the related risk factors of oral infection after chemotherapy in patients with hematological malignancies. Methods Totally 74 patients with chemotherapeutic hematological malignancies admitted from 2012-04-2015-04 in our hospital were selected as the research objects. The correlation analysis was made on the risk factors of oral infection after chemotherapy by various methods and the related preventive measures were put forward. Results The cheeks and gums were the high incidence of oral infections. The incidence of oral infections was positively correlated with most of the clinical data. The high risk factors for oral infections were age, serum albumin level below 40g / L , The absolute value of granulocytes below 0.5 × 109 L-1, poor oral environment, oral self-cleaning habits, multiple cycles of chemotherapy, chemotherapy did not alleviate several. Conclusion There are many factors that lead to oral infection after chemotherapy in patients with hematological malignancies. It is necessary to take targeted preventive measures to interfere with the factors that lead to oral infections, reduce the occurrence of oral infections and improve the quality of life of patients.