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目的：评价年龄与血清前列腺特异性抗原（PSA）水平的关系。方法：采用免疫放射分析（IRMA）测定226例正常男性各年龄组血清PSA水平。结果：30～39岁组血清PSA为（0．88±O．47）ng／ml，40～49岁组为（0．87±0．34）ng／ml，50～59岁组为（0．99±0．57）ng／ml，60～69岁组为（1．12±0．78）ng／ml，＞70岁组为（1．12±0．83）ng／ml，各组间血清PSA浓度无显著性差异（P＞0．05）。结论：当前列腺体积在正常范围内时，血清PSA水平与年龄无直接关系。
Objective: To evaluate the relationship between age and serum PSA level. Methods: Serum PSA levels were measured in 226 men with various ages by immuno-radiometric analysis (IRMA). Results Serum PSA was (0.88 ± 0.47) ng / ml in 30-39 years old group, (0.87 ± 0.34) ng / ml in 40-49 years old group, and (0 .99 ± 0.57) ng / ml, (1.12 ± 0.78) ng / ml in 60-69 years old group and (1.12 ± 0.83) ng / ml> 70 years old group, There was no significant difference between serum PSA levels (P> 0.05). CONCLUSIONS: Serum PSA levels are not directly related to age when the prostate volume is within the normal range.