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目的分析研究急性白血病患者化疗后的感染危险因素及其应对措施。方法对某院收治的急性白血病患者资料进行回顾性研究,并分析患者化疗后出现感染的危险因素以及病原体分离情况。结果 98例急性白血病患者经过化疗后64例患者出现感染,感染发生率为65.31%;感染的发生与患者的年龄、化疗时间以及患者的粒细胞数量差异有统计学意义(P<0.05);感染发生于患者的呼吸道、消化道、皮肤等部位,以革兰阴性条件致病菌为主。结论急性白血病患者化疗后极易发生感染,感染与患者的年龄、治疗时间等因素具有密切关系并以院内感染为主要类型。对急性白血病患者化疗后采取综合性的治疗措施对预防和控制感染的发生具有重要的临床意义和作用。
Objective To analyze the risk factors of infection in patients with acute leukemia after chemotherapy and its countermeasures. Methods A retrospective study was conducted on the data of patients with acute leukemia admitted to a hospital and the risk factors for infection and the isolation of pathogens after chemotherapy were analyzed. Results The infection rate was 65.31% in 98 patients with acute leukemia after chemotherapy. The incidence of infection was related to the patient’s age, chemotherapy time and the number of granulocytes in patients (P <0.05). Infection Occurred in the patient’s respiratory tract, digestive tract, skin and other parts of the main negative bacteria in Gram-negative conditions. Conclusion In patients with acute leukemia, the infection is very easy to occur after chemotherapy. The infection is closely related to the patient’s age, treatment time and other factors, and nosocomial infection is the main type. Comprehensive treatment of acute leukemia patients after chemotherapy to prevent and control the occurrence of infection has an important clinical significance and role.