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目的:探讨慢性前列腺炎并不育患者血清抗精子抗体与不育的关系,为临床治疗提供依据。方法:采用酶联免疫吸附法(ELISA)检测80例慢性前列腺炎并不育患者(A组)血清抗精子抗体(AsAb),同时选择正常生育的慢性前列腺炎患者50例(B组)作对照。结果:A组80例,检出AsAb阳性37例,阳性率46.3%,抗精子总抗体(T-Ig)(126.25±45.47)U/ml,B组AsAb阳性6例,阳性率12.0%,T-Ig(41.25±14.20)U/ml,两组阳性率及抗精子总抗体比较,差异均有统计学意义(均P<0.05)。结论:慢性前列腺炎并不育患者存在免疫性因素,ELISA方法敏感度高,操作简便,对临床合并前列腺炎的不育患者探求病因提供指导。
Objective: To investigate the relationship between serum anti-sperm antibody and infertility in infertility patients with chronic prostatitis and to provide evidence for clinical treatment. Methods: Serum anti-sperm antibody (AsAb) was detected in 80 patients with infertility due to chronic prostatitis by enzyme-linked immunosorbent assay (ELISA), and 50 patients with chronic prostatitis (control group B) . Results: In group A, 37 cases were positive for AsAb, the positive rate was 46.3%, the total anti-sperm antibody (T-Ig) was 126.25 ± 45.47 U / ml, the positive rate was 6% -Ig (41.25 ± 14.20) U / ml, the positive rate of the two groups and total anti-sperm antibody, the difference was statistically significant (P <0.05). Conclusion: There are immunological factors in patients with infertility due to chronic prostatitis. ELISA method is sensitive and easy to operate. It provides guidance for exploring the etiology of infertile patients with clinical prostatitis.