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在血气分析同时用DXC-300型红细胞变形仪测定红细胞滤过指数IF值，观察呼吸衰竭对红细胞变形能力的影响。结果：Ⅰ型呼衰19例，IF0.949±0．87，Ⅱ型呼衰33例，IFO．54±0．37。同年龄健康组IF值0．23±0．16（P＜0．01）。呼衰IF＞0．3发生率72．5％，其中Ⅰ型72．54％，Ⅱ型43．13％。健康组IF正常率85.18％（46／54例）（P＜0.01）。pH与酸碱失衡失比偿均使IF升高，但无统计学意义。17种相关因素对IF影响研究表明疾病组Hb、BUN、Cr、SB、血浆粘度、纤维蛋白原、红细胞电泳、血沉、血沉方程K值等9项具有统计学意义（P＜0.05或P＜0．01）。PCO2与Cr、红细胞电泳、Hb、血浆粘度相关系数r值分别为0．973、0．799、0.707、0.635。本组呼哀伴多脏器衰1例，ARDS1例，伴黄疸5例，心衰6例，肾功能不全11例，还有消化道出血等，病情重。因此低氧血症与高碳酸血症分别是红细胞变形能力减退的原因之一。本文对发生的机理作了讨论。
Blood gas analysis at the same time with the DXC-300 type erythrocyte deformability instrument measured the value of the erythrocyte filtration index to observe the impact of respiratory failure on erythrocyte deformability. Results: Type Ⅰ respiratory failure in 19 cases, IF0.949 ± 0.87, type Ⅱ respiratory failure in 33 cases, IFO. 54 ± 0.37. The IF of the same age group was 0.23 ± 0.16 (P <0.01). The frequency of IF> 0.3 was 72.5%, of which type Ⅰ was 72.54% and type Ⅱ 43.13%. The normal rate of IF in healthy group was 85.18% (46/54 cases) (P <0.01). The imbalance of pH and acid-base imbalances have increased IF, but not statistically significant. The influence of 17 related factors on IF showed that there were 9 statistically significant values of Hb, BUN, Cr, SB, plasma viscosity, fibrinogen, erythrocyte electrophoresis, erythrocyte sedimentation rate and erythrocyte sedimentation rate in the disease group (P <0.05 or P < .01). PCO2 and Cr, erythrocyte electrophoresis, Hb, plasma viscosity correlation coefficient r values were 0.973,0.799,0.707,0.635. This group of patients with multiple organ failure in 1 case, ARDS1 cases, with jaundice in 5 cases, 6 cases of heart failure, renal insufficiency in 11 cases, as well as gastrointestinal bleeding, severe illness. Therefore, hypoxemia and hypercapnia are one of the reasons for the decline of erythrocyte deformability. This article discusses the mechanism of occurrence.