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目的 研究有机硼类杀菌剂与强化戊二醛消毒剂混合复配后的毒性表现及强度。方法 以昆明种小鼠为实验对象,采用经口灌胃染毒,连续观察2周不同剂量组小鼠中毒症状及死亡情况,用概率单位-对数图解法计算LD_(50)及其95％可信限。结果 雄性小鼠LD_(50)为12.6g/kg,LD_(50)的95％可信限为7.4～21.4g/kg;雌性小鼠的LD_(50)为10.8 g/kg,LD_(50)的95％可信限为6.65～17.05g/kg。结论 根据消毒剂毒性分级标准规定,复配成的T901B属实际无毒级杀菌剂,且硼醛混合后无毒性协同出现,毒性明显小于T901A。
Objective To study the toxicity and strength of organoboron fungicides and fortified glutaraldehyde disinfectants. Methods Kunming mice were used as experimental subjects. Oral gavage was used to observe the symptoms and death of mice in different doses for 2 weeks. LD_ (50) and 95% Confidence limit. Results The LD 50 of male mice was 12.6 g / kg and the 95% confidence interval of LD 50 was 7.4-21.4 g / kg. The LD 50 of female mice was 10.8 g / kg, The 95% confidence limit was 6.65-17.05 g / kg. Conclusion According to the disinfectant toxicity grading standards, the compound T901B is an actual non-toxic bactericide, and the non-toxic synergistic effect of the mixture of boronic aldehyde and toxicity was significantly less than T901A.