BTLA,a New Inhibitory B7 Family Receptor with a TNFR Family Ligand

来源 :Cellular & Molecular Immunology | 被引量 : 0次 | 上传用户:li132zhihua
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B and T lymphocyte attenuator (BTLA),identified as an immune inhibitory receptor recently,plays widespreadroles on T and B cells.Emerging evidence has generated plentiful information on the mechanisms which BTLAmediates negative regulation in immune responses and involves in a variety of physiological and pathologicalprocesses.The exploration of the biological mechanisms and regulation of BTLA will open possibilities on noveltherapeutic strategies in immune-related diseases.Cellular & Molecular Immunology.2005;2(6):427-432. B and T lymphocyte attenuator (BTLA), identified as an immune inhibitory receptor recently, plays extensively on on and B cells. Emerging evidence has generated plentiful information on the mechanisms which BTLA mediates negative regulation in immune responses and involves in a variety of physiological and pathological processes The exploration of the biological mechanisms and regulation of BTLA will open possibilities on novel therapeutic strategies in immune-related diseases. Cellular & Molecular Immunology. 2005; 2 (6): 427-432.
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