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对２０１例慢性肝病行胃镜检查，１５３例（７６．１％）呈现胃、十二指肠粘膜损害。分别比较不同类型慢性肝病的胃炎、十二指肠炎与消化性溃疡的发生率：慢性活动性肝炎（ＣＡＨ）与肝炎后肝硬化（ＰＨＣ）无明显差异；而ＣＡＨ与慢性迁延性肝炎（ＣＰＨ）、ＰＨＣ与ＣＰＨ，其差异均有非常显著性。表明肝病越活动，越严重，粘膜损害越明显；提示肝─胃之间可能存在因果关系，与祖国医学＂肝胃不和＂之说颇为相似。同胃十二指肠疾病组（胃病组）比较，慢性肝病并胃十二指肠疾病组（肝胃组）腹痛少见（占２０．３％），上消化道出血多见（占７５．８％），食管胃底静脉曲张破裂常见（占６２．９％），三者差异均有非常显著性意义。值得一提的是：肝胃组胃粘膜糜烂和溃疡活跃出血达３７．１％，易诱发肝昏迷死亡（占３４．９％）．此外，对粘膜损害的机理也作了初步探讨。
201 cases of chronic liver disease by gastroscopy, 153 cases (76.1%) showed gastric and duodenal mucosal damage. The incidence of gastritis, duodenitis and peptic ulcer in different types of chronic liver diseases were compared respectively: no significant difference was found between chronic active hepatitis (CAH) and posthepatitic cirrhosis (PHC); while CAH was associated with chronic persistent hepatitis (CPH) , PHC and CPH, the differences were very significant. That the more active liver disease, the more serious mucosal damage more obvious; suggesting that there may be a causal relationship between liver and stomach, and the motherland medicine “liver and stomach discordant” is quite similar. Compared with the gastroduodenal disease group (stomach group), chronic liver disease and gastroduodenal disease group (liver and stomach group) had rare abdominal pain (20.3%) and upper gastrointestinal bleeding (75.8% %), Esophageal varices common (62.9%), the three differences were very significant. It is worth mentioning that: liver and stomach gastric mucosal erosion and ulcer active bleeding reached 37.1%, easily lead to hepatic coma deaths (34.9%). In addition, the mechanism of mucosal damage is also made a preliminary study.