论文部分内容阅读
目的:比较雷莫司琼和托烷司琼预防口腔颌面外科术后恶心、呕吐的效果。方法:选择120例ASAⅠ～Ⅱ级择期行口腔颌面外科手术的患者,随机分为3组,在麻醉诱导前静脉注射雷莫司琼(R组,n=40)0.3mg、托烷司琼(T组,n=40)5mg、生理盐水(对照组,C组,n=40)5mL。观察术后24h内恶心、呕吐的发生情况,采用SPSS 11.0软件包对数据进行χ2检验。结果:术后24h内,恶心、呕吐的发生率R组和T组显著低于C组,差异有统计学意义(P<0.05),R组和T组比较差异无统计学意义(P>0.05)。结论:雷莫司琼和托烷司琼均可显著减少术后恶心、呕吐的发生率,两者疗效相当。
Objective: To compare the effect of ramosetron and tropisetron on prevention of nausea and vomiting after oral and maxillofacial surgery. Methods: One hundred and twenty patients with ASA Ⅰ ~ Ⅱ elective oral and maxillofacial surgery were randomly divided into three groups: 0.3 mg ramosetron (R group, n = 40), tropisetron (T group, n = 40) 5mg, saline (control group, C group, n = 40) 5mL. The incidence of nausea and vomiting within 24 hours after operation was observed. The data were analyzed by χ2 test using SPSS 11.0 software package. Results: Within 24 hours after operation, the incidence of nausea and vomiting was significantly lower in group R and group T than in group C (P <0.05), but there was no significant difference between group R and group T (P> 0.05 ). Conclusion: Both ramosetron and tropisetron can significantly reduce the incidence of postoperative nausea and vomiting, both of which have similar efficacy.